Antibody therapy may be useful in Alzheimer’s disease – DiarioMedico.com

Diariomedico.com
Spain
THE MOLECULES are more effective
Antibody therapy may be useful in Alzheimer’s disease
Some antibodies specifically designed to go beyond the blood-brain barrier would improve the treatment of Alzheimer’s disease, according to Science Translational Medicine published today.

Updated – Thursday, 26 May 2011 – drafting to 00: 00 h.

Two studies published today in Science Translational Medicine show how to improve the effectiveness of drugs against Alzheimer’s disease; to this end, some antibodies specifically designed are used. These molecules Act by blocking one of the enzymes needed to produce peptide amyloid beta, to add in the brain of patients with Alzheimer’s disease induced Neurodegeneration.

Researchers have designed the antibody so it ligue a recipient of the blood-brain barrier; Unlike other antibodies, the new molecule not binds to transferrin, another recipient of blood-the brain barrier that moves by the blood vessels, without reaching the brain tissue. Thanks to these new antibodies do not have a high affinity for transferrin, can overcome the blood-brain barrier and reach the brain without getting lost along the way; Instead, bind to the enzyme beta secretasa (BACE1), which is a therapeutic target in Alzheimer’s disease.

In fact, as they have seen these researchers in models of the disease in mice and monkeys, there is a reduction in the amount of amyloid peptides in the blood of animals, as well as in the brain, although the latter is more modest. Despite these findings, clinical studies to determine whether the efficacy seen in experimental models reproduces in patients are needed.

Both works have been made by the Group of Ryan j. Watts, of the Department of neuroscience of the biotechnological Genentech, based in San Francisco, and by the team of Mark S. Dennis, of the Department of engineering of antibodies, the aforementioned company. The works are accompanied by an editorial, in Steven M. Paul, at Cornell University (New York), also in this issue of the magazine, on the implications of this type of therapy

(Science Trans Medicine 2011; 3: 84ra43/84ra44).
Antibody therapy may be useful in Alzheimer’s disease – DiarioMedico.com

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If cooked correctly, the fish may be beneficial for the heart of the woman: MedlinePlus

If cooked correctly, the fish may be beneficial for the heart of the woman
A study is to eat it roasted on the grill or oven-baked reduced the risk of heart failure in 30 per cent

Address of this page:
(http://www.nlm.nih.gov/medlineplus/spanish/news/fullstory_112472.html(*estas news will not be available after 08/23/2011)

Translated from the English: Wednesday, may 25, 2011

Topics on MedlinePlus

In women’s heart disease
Heart failure
Nutrition

Tuesday, May 24 (HealthDay News/HolaDoctor) according to a recent study, the fish, known for some time to be healthy for the heart, when it baked or roasted on the Grill also protects against the development of heart failure.

The research, which followed up more than 84,000 postmenopausal women for an average of 10 years, found that those whose diets included more fish baked and roasted on the grill is to say, five or more servings a week had a risk of heart failure 30 percent lower, compared with women who ate less than one serving per month.

“A direct link between fish and heart failure is not necessarily intuitive because it might be expected to protect against heart attacks,” said the lead author of the study, Dr. Donald Lloyd, a preventive cardiologist and director of the Department of preventive medicine of the Faculty of medicine Feinberg of Northwestern University, in Chicago. “But this is not the mechanism that operates here and I think that is something interesting.” “It is also interesting that the way in which the fish is prepared is as important as the type of fish consumed”.

The study appears published on 24 may in the journal Circulation: Heart Failure.

According to the study, eating fried fish, which previously was associated with increased risks of stroke, is associated with a greater risk of heart failure, and a single serving per week was associated with a risk increased 48 percent.

In addition, dark as the salmon, the macarellus and anchovy fish were associated with risks lower than those who represent either tuna or white fish such as sole, sea bream or COD.

According to previous research, fatty acids omega 3 present in fish reduced the risks of cardiovascular disease to reduce inflammation and improve the blood pressure, as well as the function of the heart and blood vessels.

Lloyd commented that their study not revealed a specific relationship between fatty acids omega 3, and heart failure, compared with heart disease in general, but pointed out that the science continues unraveling all the nutritional aspects of fish. Heart failure is characterized by the inability of the heart to pump blood to the rest of the body.

“It is possible that we do not know the other components but that is the reason why eating fish is better than taking a supplement,” he said. “It is really necessary to consume food.” “This is undoubtedly an important part of a healthy eating pattern”.

The study of Lloyd was based on data from 84,493 women aged 50 to 79 who were part of the study Women’s Health Initiative (initiative of women’s health). The vast majority of the participants were white (85 percent), while 7 per cent were African American and 3% Hispanic.

The main limitation of the study was its nature of observation and the fact of the own participants to inform about their eating habits, said Lona Sandon, Assistant Professor of clinical nutrition from University of Texas Southwestern, Dallas.

“You don’t know is if these women have been eating five servings of fish baked or roasted grilled throughout his life, or if it is something that began to make from age 50,” said Sandon. “It is also possible that they have a more active lifestyle and consume less saturated fat.” “So there are probably many differences in the general nutritional intake”.

In fact, the study showed that the participants whose diets included more baked and roasted grilled fish used to be healthier and look younger than their counterparts who ate fish fried, that they were more physical activity and had a better physical condition. In addition, they were more educated, less likely to smoke and showed reduced incidence of diabetes, high blood pressure and cardiovascular disease.

“Undoubtedly is promising that [fish baked and roasted on the grill] essentially had a protective effect,” said Sandon. “That corresponds to what we know from other studies: the fish contains something that is good for us.” “And not fried fish also contains something that is good for us.”

Article by HealthDay, translated by Hispanicare
SOURCES: Donald Lloyd, M.D., preventive cardiologist and director of the Department of preventive medicine of the Faculty of medicine Feinberg of Northwestern University, Chicago; Lona Sandon, R.D., Assistant Professor of clinical nutrition from University of Texas Southwestern Medical Center, in Dallas; May 24, 2011, Circulation: Heart Failure

HealthDay
(c) copyrights 2011, HealthDay
If cooked correctly, the fish may be beneficial for the heart of the woman: MedlinePlus

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ORLive, Inc. and U.S. National Library of Medicine: La reparación cardiaca de un PFO

Heart of a persistence of Patent foramen ovale repair (PFO, for its acronym in English)
Tue, 24 May 2011 14: 54: 31-0500

ORLive, Inc. and U.S. National Library of Medicine: a PFO heart repair

Congenital heart defects

Address of this page: http://www.nlm.nih.gov/medlineplus/spanish/congenitalheartdefects.html

Other names: heart of birth defects

A congenital heart defect is a problem with the structure of the heart. It is present at the time of birth. Congenital heart defects are the most common type of major birth defects.

The heart of an infant begins to develop shortly after conception. During development, structural defects may occur. These defects may affect the walls of the heart, heart valves, arteries and veins close to the heart. Congenital heart defects can disrupt the normal flow of blood through the heart. The flow can be:

Slow ?Hacerse
?IR in the wrong direction or the wrong place
Completely blocked ?estar

Treatment of the defect may include medicines, surgery and other medical procedures and heart transplants. Treatment depends on the type and severity of the defect and of the age, size and the overall health of the child. Today, many children born with complex congenital heart defects grow to adulthood and lead productive lives.

NIH: National heart, lung, and Blood Institute

MedlinePlus page of multiple access:
Congenital heart defects: MedlinePlus in Spanish

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Carpal tunnel syndrome is cultural?: MedlinePlus

Is carpal tunnel syndrome cultural?

Address of this page:
(http://www.nlm.nih.gov/medlineplus/spanish/news/fullstory_112496.html(*estas news will not be available after 08/23/2011)

Translated from the English: Wednesday, may 25, 2011
Topic on MedlinePlus

Carpal tunnel syndrome

NEW YORK (Reuters) – each year, more than four out of every 1,000 Swedish women are diagnosed with the syndrome of the carpal tunnel, a number much lower than that recorded in United States, revealed a study carried out in Sweden.

In males, the number of new cases remained just below the two of every 1,000, according to research led by Isam Atroshi, of the Hassleholm Hospital in Sweden, and published in Archives of Internal Medicine.

Carpal tunnel syndrome is a painful condition caused by a clamping to a nerve in the wrist. Although sometimes it will only, may require treatment, and possible surgery to relieve pressure on the nerve if they fail to splinting or corticosteroid hormone injections.

“Some studies estimated the incidence of the syndrome of the carpal tunnel (STC), showing wide differences between countries,” he wrote Atroshi.

“We believe the impact of the STC diagnosed by doctors and the surgeries in the general population in the South of Sweden and compare it with the general population of United States,” he added.

Previous studies have produced similar results.

One, in which participated Gelfman Russell of the clinic may, revealed that about twice as many people in the County of Olmsted, Minnesota, were diagnosed with carpal tunnel, compared with the observed rates in Sweden.

“This study adds to our comments that there are differences in the incidence of clinically attended carpal tunnel syndrome and surgical treatment between countries,” he told Reuters Health Gelfman, who did not participate in the recent study.

It is still unknown what is behind these differences, but both medical factors such as social, could affect wrote Atroshi.

For example, it could be related to obesity or various types of work, added the author.

Carpal tunnel often occur as a result of repetitive movements that cause inflammation in the ligaments of the wrist and pinzan nerve.

Gelfman reported that up to 15 percent of the population would have symptoms, but only around 5 per cent or less is diagnosed with carpal tunnel syndrome.

Reuters Health
? 2011 Thomson Reuters. All rights reserved. The Reuters content are intellectual property of Thomson Reuters and/or its content providers. The content of these pages may not copied, published, or redistribute partially or fully, without the prior consent in writing of Thomson Reuters. Thomson Reuters will not be responsible for errors or delays in the content. “reuters” and its logo are either registered trademarks or trademarks of the Group of companies of Thomson Reuters around the world. For more information on other Reuters media products please visit http://about.reuters.com/media/. ? Thomson Reuters 2011
Carpal tunnel syndrome is cultural?: MedlinePlus

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Nature’s Cure Two-Part Acne Treatment System, for Women, 1 month supply (60 Tablets, 1 Ounce Cream)

Posted by cshack on May 27, 2011 at 1:06 pm · Under acne remedies

(Product received may temporarily differ from image shown due to packaging update. Image will be revised, shortly)
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They do not increase sun-sensitivity and have no side effects.

Topical Acne Medication – Vanishing Cream: To clear existing blemishes, Nature’s Cure has a colorless, unscented, greaseless, 5% Benzoyl Peroxide cream. Nature’s Cure Vanishing Cream also contains aloe vera concentrate and allantoin to moisturize and soothe the skin.
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They counteract the symptoms of Parkinson’s disease with Tai Chi classes – NYTimes.com

Rehabilitation / initiative for the neurological society of Argentina
They counteract the symptoms of Parkinson’s disease with Tai Chi classes
Given its proven benefits, recommended practice it as early as possible
Wednesday, may 25, 2011 | Published in print edition.
Fabiola Czubaj
THE NATION

Although it may seem strange, slow movements, paused and coordinated an ancient Chinese physical discipline such as Tai Chi are ideal for people with Parkinson’s. Moreover, such is the relaxation that generated that, little by little, the session manages to begin to fade one of the most well known symptoms of the disease, tremor.

“The practice of Tai Chi in people with Parkinson’s is very innovative, as they are other secondary therapies in rehabilitation (tango or yoga).” “In this case, they should concentrate in order to slow and very measured, movements that improve the elongation and coordination, and allow them to counter the classic symptoms of the disease, which are the rigidity, tremor, or involuntary movements (dyskinesias)”, explained Dr. Cecilia Peralta, of the Group of unusual movements and Parkinson of the Argentina neurological society (NSS).

And this was the case with more than 50 patients in a Tai Chi session during a meeting organized by a program of SNA that promotes the exercise overseen in people living with the disease, which affects nerve cells in an area of the brain known as substance nigra and that control muscle movements. Therefore people with Parkinson’s are losing expressiveness in the face, move hand more slowly, write with a smaller font or walk dragging your feet.

“As they are losing some balance and postural reflexes, all physical therapies to stimulate the re-education of the posture and balance, such as Tai Chi, will to succeed only if done them in a sustained manner, i.e. weekly or daily – said the doctor Diego Bauso”, of the same working group. “And sometimes even complement each other very well drug treatment.”

It is that, according to agreed Peralta, Bauso and Dr. Nélida Garretto, driving the Parkinson programme in movement, it is common think patients and may be much less than it really can. “This kind of exercises in controlled environments allow them to develop certain skills that are latent,” it added Bauso.

That Yes, consistency is the key: “When they stop doing the exercise, the benefit is lost – said the expert-.” “If they are constant, the benefits are clear.” The list includes the improvement of postural control, which is affecting more moderate or advanced stage disease and predisposes to drops. To recover the balance and the orientation is another positive effect, according to motor assessment scales.

In fact, these results changed medical practice. “When we send patients to perform traditional physical rehabilitation, is high drop-out – noted Garretto-.” “With Tai Chi, as with tango, we see that this is not true and that to stimulate the social exchange.”

But that’s not all. “We indicated earlier, the rehabilitation in more advanced cases of the disease”. “Now, do so as soon as possible”, said Peralta. It is that, as you pointed out Bauso, start doing these exercises at the initial stage of Parkinson’s disease “improves its evolution”.

Ten minutes a day

For nearly an hour, the leisurely and gentle voice of the instructor led the slow movements with which more than 50 people made different figures body in one of the salons of the circle sea officers. In the end, the instructor advised them: “repeat these exercises at home, 10 minutes in the morning.” “With a little every day, a month will go better.”

Eleodoro, of 68 years, that it co-exists with Parkinson’s for 6 years and never stopped working in the bakery, ended the session without visible tremor in hands and relaxed. “I am relieved – he said-.” “We have little stability, but here not we got, so it is worth trying it, do not…?”

Elena frameworks, 58 years and neighbor of Lincoln, it was all new. “Do not know, and that I test everything I can.” I’m starting to lose their balance and here I noticed no. “It gives agility and sense of serenity, which is what we need to be well.”

Tai Chi does not increase the heart rate or the natural shaking of the body, explained Garretto. “As the tremor in Parkinson’s disease is closely related to anxiety and emotional stress, it is a symptom which improves.” “The patients apply relaxation techniques at any time,” he concluded. For more information about the program, info@sna.org.ar.

They counteract the symptoms of Parkinson’s disease with Tai Chi classes – NYTimes.com

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Nexcare Skin Crack Care .24 fluid ounces (7-ml)

Posted by cshack on May 27, 2011 at 9:49 pm · Under acne remedies

Nexcare Skin Crack Care is designed for painful skin cracks to promote healing for dry, cracked skin on fingers, hands, feet, and elbows. Easy-to-use, fast-drying, clear liquid. Forms a long-lasting, waterproof seal to protect extremely dry skin. Contains natural ingredients: Vitamin C, Vitamin E and Tea Tree Oil.

Price: $10.99

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